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In comic books published by Marvel Comics, a mutant is an organism (usually otherwise human) who possesses a genetic trait called an X-gene that allows the mutant to naturally develop superhuman powers and abilities. Human mutants are considered to be of the subspecies Homo sapiens superior, an evolutionary progeny of Homo sapiens, and are considered the next stage in human evolution, though whether this is true or not is a subject of much debate in-universe.

Unlike Marvel's mutates, which are characters who develop their powers only after exposure to outside stimuli or energies (such as the Hulk, Spider-Man, The Fantastic Four, and Absorbing Man), mutants are born with the genetic potential to possess their powers, although the powers typically manifest at puberty.

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